What Is Medicinal Cannabis?

Medicinal cannabis, often referred to as medical marijuana, is a category of legal, high-quality medicines that can be prescribed by qualified healthcare professionals to treat various medical conditions and alleviate the side effects of certain treatments. This therapeutic approach involves the use of cannabis-derived products that have been carefully developed and regulated to ensure safety and efficacy.

Medicinal cannabis is derived from the Cannabis sativa or Cannabis indica plants, and it contains a range of chemical compounds known as ‘cannabinoids.’ Researchers have identified between 80 and 100 different cannabinoids in medicinal cannabis, and ongoing scientific investigations aim to understand the specific properties and potential benefits of each of these compounds.

Currently, the two most well-known and studied cannabinoids found in medicinal cannabis are cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC). These cannabinoids play a central role in the therapeutic effects of medicinal cannabis.

CBD is often praised for its non-psychoactive nature, meaning it doesn’t produce the “high” typically associated with cannabis use. Instead, it offers potential benefits such as pain relief, reduction of inflammation, and management of various medical conditions.

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THC, on the other hand, is the primary psychoactive compound in cannabis. While it can produce a “high” in some individuals, it also possesses therapeutic properties, such as pain management, nausea control, and appetite stimulation. In some cases, THC and CBD are used together to create a balanced therapeutic effect.

It’s important to note that the specific composition of medicinal cannabis products can vary widely, with different ratios of CBD and THC and other cannabinoids and terpenes. These variations allow healthcare professionals to tailor treatment plans to the unique needs of individual patients and their medical conditions.

Medicinal cannabis has shown promise in the treatment of various conditions, including chronic pain, epilepsy, multiple sclerosis, cancer-related symptoms, and certain mental health disorders. However, its use is subject to legal regulations and varies by region, so patients should consult with healthcare professionals who are knowledgeable about its availability and prescription guidelines in their area.

As the field of medicinal cannabis research continues to evolve, our understanding of its potential benefits and applications will expand. This natural remedy has the potential to provide relief and improve the quality of life for individuals facing a range of medical challenges.

What Can Medicinal Cannabis Be Used For?

Medicinal cannabis, derived from the cannabis plant, is being explored as a therapeutic option for various medical conditions, although formal evidence is still evolving. While doctors have historically lacked extensive clinical data to guide their decisions, some evidence suggests that certain medicinal cannabis products may be beneficial in the treatment of specific medical conditions and symptoms. Here are some of the conditions and situations where medicinal cannabis may have a potential role:

1. Epilepsy: One of the most well-established uses of medicinal cannabis is in the treatment of epilepsy, particularly in cases where traditional anti-seizure medications have proven ineffective. Certain cannabis-derived products, particularly those high in cannabidiol (CBD), have shown promise in reducing the frequency and severity of seizures in some individuals with epilepsy.

2. Multiple Sclerosis: Medicinal cannabis is being explored as a treatment option for multiple sclerosis (MS). Some research suggests that it may help manage symptoms such as muscle spasms, pain, and spasticity in individuals with MS.

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3. Cancer and Cancer Treatment Symptoms: Medicinal cannabis may provide relief from symptoms associated with cancer and its treatments. These symptoms can include nausea and vomiting induced by chemotherapy, cancer-related pain, and loss of appetite. Cannabis-based products, such as oral sprays or capsules, have been investigated for their potential to alleviate these side effects and improve the quality of life for cancer patients.

4. Pain Management: Chronic pain is a complex and challenging medical issue that can be difficult to treat effectively. Some individuals with chronic pain conditions, such as neuropathic pain or musculoskeletal pain, have reported symptom relief with medicinal cannabis. It may offer an alternative or complementary approach to pain management.

5. Symptom Relief in Palliative Care: In palliative care settings, where the focus is on improving the quality of life for individuals with serious illnesses, medicinal cannabis may play a role in symptom relief. It can help manage pain, alleviate nausea and vomiting, and address other discomforts associated with advanced diseases.

It’s important to note that the use of medicinal cannabis should always be guided by a qualified healthcare professional. In many regions, doctors or specialists can apply for government approval to prescribe medicinal cannabis for various medical conditions. However, this process typically requires them to provide evidence supporting the potential effectiveness of medicinal cannabis for the specific condition being treated.

The field of medicinal cannabis research is continuously evolving, and ongoing studies aim to provide more comprehensive data on its efficacy and safety for various medical conditions. Patients and healthcare professionals interested in exploring medicinal cannabis as a treatment option should consult with experts who have experience in its prescription and use. Additionally, government agencies and medical organizations may provide resources and guidelines to support medical professionals in prescribing medicinal cannabis appropriately.

Types and Forms of Medicinal Cannabis

Medicinal cannabis is available in various types and forms, each with its characteristics and applications. The choice of which form to use depends on factors like the patient’s condition, treatment goals, and legal regulations. Here are the primary types and forms of medicinal cannabis:

1. Pharmaceutical Cannabis Products: These are medicinal cannabis products that have undergone rigorous testing, quality control, and regulatory approval by organizations like the Therapeutic Goods Administration (TGA) in Australia. Examples include:

   – Nabiximols (Sativex®): Sativex is an approved pharmaceutical cannabis product available in over 24 countries. It is primarily used to treat spasticity due to multiple sclerosis. Sativex is administered as a nasal or oral spray, providing precise dosing and consistency.

   – Synthetic Cannabinoids (e.g., Dronabinol®): Synthetic cannabinoids are lab-produced compounds that mimic the effects of naturally occurring cannabinoids found in the cannabis plant. Dronabinol is an example and is used for various medical purposes, including managing nausea and vomiting associated with chemotherapy and stimulating appetite in HIV/AIDS patients.

2. Controlled and Standardized Herbal Cannabis (Plant Products): In some regions, particularly the Netherlands, controlled and standardized herbal cannabis products are available. These are derived directly from the cannabis plant, and their composition is carefully regulated to ensure consistent cannabinoid content and quality. This form allows for the natural benefits of the whole cannabis plant to be harnessed in a controlled manner.

3. Unregulated and Illegal Herbal Cannabis (Plant Products): In some areas, particularly in the United States, unregulated and illegal herbal cannabis is available for medicinal use. This form poses significant challenges as it lacks quality control, standardized dosing, and regulatory oversight. The cannabinoid concentrations can vary widely, and there may be concerns about contaminants such as bacteria and mold. Patients using this form of cannabis should exercise caution and be aware of the legal and health risks associated with its use.

Patients and healthcare providers need to work together to determine the most appropriate type and form of medicinal cannabis for a specific medical condition. Regulatory authorities in each country may have their own guidelines and approval processes for accessing medicinal cannabis. Safety, quality, and consistency are paramount considerations when using medicinal cannabis, and choosing pharmaceutical-grade products or controlled herbal cannabis can help ensure these standards are met. Additionally, ongoing research aims to expand the range of available medicinal cannabis products and improve our understanding of their effectiveness for various medical conditions.

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Benefits of Medicinal Cannabis

While the research on medicinal cannabis is ongoing, it has shown promise in providing benefits, especially for individuals with chronic or terminal illnesses who may not find relief from conventional medicines. Here are some potential benefits and areas of research for medicinal cannabis:

1. Chronic and Terminal Illness Relief: Medicinal cannabis may offer relief to individuals suffering from chronic or terminal conditions when conventional treatments have not been effective. It can help manage symptoms and improve the quality of life for these patients.

2. Alleviating Side Effects: Medicinal cannabis has been found to alleviate side effects caused by other medications. For example, it can help reduce nausea and vomiting in patients undergoing chemotherapy, making cancer treatment more tolerable.

3. Epilepsy: One of the most well-established uses of medicinal cannabis is in the treatment of epilepsy, particularly certain forms of epilepsy that do not respond to traditional antiepileptic drugs. Cannabidiol (CBD), a non-psychoactive compound in cannabis, has shown promise in reducing the frequency and severity of seizures.

4. Multiple Sclerosis (MS): Medicinal cannabis has been investigated as a potential treatment for the symptoms of multiple sclerosis, including muscle spasms and spasticity. Some pharmaceutical cannabis products, like Sativex, have been approved for this purpose in certain countries.

5. Non-Cancer Chronic Pain: Chronic pain conditions that do not respond well to other treatments are being explored as potential candidates for medicinal cannabis use. Cannabis may help alleviate pain and improve the overall well-being of individuals with conditions like neuropathy and arthritis.

6. Palliative Care: In palliative care, medicinal cannabis may provide relief to patients suffering from severe pain, nausea, and other distressing symptoms associated with advanced illness. It can enhance the comfort and quality of life for those in palliative care.

It’s important to note that while there is growing evidence supporting the use of medicinal cannabis for these conditions, more research is needed to fully understand its effectiveness, safety, and long-term effects. Additionally, the use of medicinal cannabis should always be guided by healthcare professionals, and patients should consider the legal and regulatory aspects of accessing and using these products in their respective regions. The field of medicinal cannabis research continues to evolve, and ongoing studies aim to provide a clearer picture of its potential benefits and risks.

Also Read: CBD and THC

Can I Get a Prescription for Medicinal Cannabis?

In England, obtaining a prescription for medicinal cannabis is a process that is currently limited to specific medical conditions and circumstances. Here are some key points to consider:

1. Limited Availability: Very few individuals in England are likely to receive a prescription for medicinal cannabis. The use of medicinal cannabis is highly regulated and only considered for specific medical conditions.

2. Approved Conditions: Medicinal cannabis prescriptions in England are typically considered for the following conditions:

   – Children and adults with rare, severe forms of epilepsy.

   – Adults experiencing vomiting or nausea as a side effect of chemotherapy.

   – People with muscle stiffness and spasms due to multiple sclerosis (MS).

3. Last Resort: Medicinal cannabis is usually considered when other treatments have proven to be ineffective or unsuitable for the patient’s condition.

4. Epidiolex for Epilepsy: Epidiolex is a highly purified liquid containing CBD (cannabidiol) and is used in the treatment of rare forms of epilepsy, such as Lennox-Gastaut syndrome and Dravet syndrome. CBD is a non-psychoactive component of cannabis, meaning it does not produce a “high.”

5. Nabilone for Chemotherapy: Nabilone, a capsule medication designed to act similarly to THC (the psychoactive component of cannabis), may be prescribed to adults undergoing chemotherapy to relieve nausea and vomiting when other treatments have not been effective.

6. Nabiximols (Sativex) for MS: Nabiximols, sold under the name Sativex, is a cannabis-based oral spray approved for adults with MS-related muscle spasticity that has not improved with other treatments.

7. Long-Term Pain: While there is some evidence suggesting that medicinal cannabis may be beneficial for certain types of pain, the evidence is not yet strong enough to recommend it as a primary treatment for pain relief.

It’s important to note that the availability and eligibility for medicinal cannabis prescriptions may vary by region and are subject to change as further research and clinical trials are conducted. Patients seeking medicinal cannabis should consult with a specialist or healthcare provider to determine if it is a suitable option for their specific medical condition and to navigate the regulatory requirements associated with its prescription.

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Side Effects of Medicinal Cannabis

Medical cannabis, like any medication, can potentially lead to side effects. The specific side effects can vary depending on the type of medical cannabis being used. Here are some possible side effects associated with medicinal cannabis:

1. Decreased Appetite: Some individuals may experience a reduced appetite as a side effect of using medical cannabis.

2. Diarrhea: Diarrhea is another possible side effect that can occur in response to medical cannabis treatment.

3. Nausea: Feeling sick or experiencing nausea is a potential side effect for some patients using medicinal cannabis.

4. Weakness: Weakness or a sense of reduced physical strength may be reported by individuals using medical cannabis.

5. Behavioral or Mood Changes: Medical cannabis can sometimes lead to changes in behavior or mood in certain patients.

6. Dizziness: Dizziness is a common side effect associated with the use of medicinal cannabis.

7. Fatigue: Feeling very tired or experiencing fatigue is another possible side effect.

8. Feeling High: Some individuals may feel a sense of euphoria or “high” when using medical cannabis, particularly if the product contains THC (tetrahydrocannabinol).

9. Hallucinations: In some cases, hallucinations or altered perceptions may occur as a side effect of medicinal cannabis.

10. Suicidal Thoughts: While rare, some individuals may experience suicidal thoughts as a side effect. It is essential to seek immediate medical attention if this occurs.

If you encounter any side effects while using medicinal cannabis, it is crucial to communicate these experiences with your medical team or healthcare provider. They can provide guidance on how to manage these side effects and may adjust your treatment plan if necessary.

Additionally, it’s important to be aware that both CBD and THC, the primary cannabinoids in medical cannabis, can potentially interact with other medications you may be taking. Always discuss possible drug interactions with a specialist to ensure the safety and effectiveness of your treatment.

Furthermore, CBD can impact liver function, so regular monitoring by healthcare professionals is essential for patients using medicinal cannabis. Monitoring helps ensure that any potential adverse effects on liver function are identified and addressed promptly. If you experience side effects or have concerns about your treatment, don’t hesitate to consult with your medical team for guidance and support. Reporting side effects through established channels, such as the Yellow Card Scheme, can also contribute to the overall safety of medicinal cannabis use.

FAQs

Q. What is medicinal cannabis?

A. Medicinal cannabis, also known as medical marijuana, refers to high-quality medicines derived from the cannabis plant. Healthcare professionals can prescribe these products to treat medical conditions and manage treatment-related side effects. It contains cannabinoids, with cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) being the most well-known.

Q. What conditions can medicinal cannabis be used for?

A. Medicinal cannabis is explored as a treatment option for conditions like epilepsy (especially when other treatments fail), multiple sclerosis, cancer-related symptoms (nausea, pain), chronic pain, and symptom relief in palliative care.

Q. What are the types and forms of medicinal cannabis?

A. Medicinal cannabis comes in various forms, including pharmaceutical cannabis products (e.g., Sativex, synthetic cannabinoids), controlled herbal cannabis (in some regions), and unregulated herbal cannabis (in some areas of the U.S.). The choice depends on factors like the patient’s condition and legal regulations.

Q. What are the benefits of medicinal cannabis?

A. Medicinal cannabis may provide relief for chronic and terminal illnesses, alleviate side effects of other medications, manage epilepsy, treat multiple sclerosis symptoms, address non-cancer chronic pain, and enhance comfort in palliative care.

Q. Can I get a prescription for medicinal cannabis in England?

A. Medicinal cannabis prescriptions in England are limited to specific conditions, such as rare forms of epilepsy, chemotherapy-induced nausea, and muscle stiffness due to multiple sclerosis. It’s typically considered when other treatments are ineffective or unsuitable.

Q. What are the side effects of medicinal cannabis?

A. Side effects may include decreased appetite, diarrhea, nausea, weakness, mood changes, dizziness, fatigue, feeling high (especially with THC), hallucinations (rare), and in rare cases, suicidal thoughts. CBD and THC can interact with other medications.

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